Electrocerebral inactivity (ECI) on EEG

ECI · Coma

Flat at standard gain. At 2 µV/mm only ECG artefact and electrode noise remain. Simulated trace, longitudinal bipolar channels. Open in the interactive viewer

What it looks like

No cerebral activity above 2 µV when recorded to a strict technical standard: at least eight scalp electrodes, inter-electrode distances of at least 10 cm, impedances between 100 Ω and 10 kΩ, sensitivity of 2 µV/mm, at least 30 minutes, with no reactivity to intense stimulation. 5

What it means at the bedside

ECI is not specific for death: sedative overdose and hypothermia produce it reversibly. Brain death is a clinical determination. The 2023 AAN/AAP/CNS/SCCM guideline no longer accepts EEG as an ancillary test; requirements differ between countries, so follow your national protocol. 6 In the viewer, raise the sensitivity to 2 µV/mm: what remains is ECG artefact.

ComaTechnical standard

Sources

  1. Stecker MM, et al. ACNS Guideline 6: Minimum technical standards for EEG recording in suspected cerebral death. J Clin Neurophysiol 2016;33:324–327. doi.org/10.1097/WNP.0000000000000322
  2. Greer DM, et al. Pediatric and adult brain death/death by neurologic criteria consensus guideline (AAN, AAP, CNS, SCCM). Neurology 2023;101:1112–1132. doi.org/10.1212/WNL.0000000000207740

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